Hey and Welcome,
First thing I would do is open up the case and check the power and IDE ribbon cables going to the CD-ROM. Also check the IDE ribbon cable at the motherboard. You're looking for secure fit with everything.
Have you been inside the case lately for any reason? If so, you may have disturbed one of the cables mentioned above.
Post back with progress on the above. However, if everything is secure and it was working before, it might be that the CD-ROM unit is dirty, which would not allow the heads to move and read correctly. If you want to try cleaning it yourself, post back and some others can give you the necessary steps involved.
Big Blue 66
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